• Anti-Infective Effect of Adhesive Probiotic Lactobacillus in Fish is Correlated with Their Spatial Distribution in the Intestinal Tissue 

      He, Suxu; Ran, Chao; Qin, Chubin; Li, Shuning; Zhang, Hongling; de Vos, Willem M.; Ringø, Einar; Zhou, Zhigang (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-16)
      In this study, we tested the distribution of 49 Lactobacillus strains in the mucus and mucosa of the intestine tissue of zebrafish. We observed a progressive change in the spatial distribution of Lactobacillus strains, and suggested a division of the strains into three classes: mucus type (>70% in mucus), mucosa type (>70% in mucosa) and hybrid type (others). The hybrid type strains were more efficient ...
    • Gender-specific associations between saliva microbiota and body size 

      Raju, Sajan C.; Lagström, Sonja; Ellonen, Pekka; de Vos, Willem M.; Eriksson, Johan G.; Weiderpass, Elisabete; Rounge, Trine Ballestad (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-10)
      <i>Objective</i>: The human intestinal microbiota likely play an important role in the development of overweight and obesity. However, the associations between saliva microbiota and body mass index (BMI) have been sparsely studied. The aim of this study was to identify the associations between saliva microbiota and body size in Finnish children.<p> <p><i>Methods</i>: The saliva microbiota of ...
    • Reproducibility and repeatability of six high-throughput 16S rDNA sequencing protocols for microbiota profiling 

      Raju, Sajan C.; Lagström, Sonja; Ellonen, Pekka; de Vos, Willem M.; Eriksson, Johan Gunnar; Weiderpass, Elisabete; Rounge, Trine Ballestad (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-18)
      Culture-independent molecular techniques and advances in next generation sequencing (NGS) technologies make large-scale epidemiological studies on microbiota feasible. A challenge using NGS is to obtain high reproducibility and repeatability, which is mostly attained through robust amplification. We aimed to assess the reproducibility of saliva microbiota by comparing triplicate samples. The ...